師資
個人簡介
郭瓊玉，副教授，博士生導師。長期注重于高分子生物材料在轉化醫學方向的研發，將其應用于多個具有挑戰性的生物醫學課題，在可移植人工角膜、介入栓塞材料、長效藥物控釋、記憶性納米材料以及細胞調控等領域里取得了突出的研究成果。郭瓊玉教授是深圳市海外高層次人才“孔雀計劃”B類獲得者，發表學術論文>40篇，被引用>1200次，申請專利15項，授權11項，其中可移植人工角膜和形狀記憶微納材料的研究成果在全球提交了多項專利申請，已經獲得包括中國、美國、日本和歐洲等多個國家的專利授權；撰寫專著和章節2部；現任中國醫師協會介入醫師分會第三屆委員會介入醫學工程與生物技術學組委員、廣東省生物醫學工程學會智能介入醫學分會常務委員、深圳市生物醫學工程學會生物醫學材料專業委員會常委。
教育背景
2004年-2010年 美國凱斯西儲大學高分子工程 博士
1999年-2004年 中國科技大學高分子工程 學士
工作經歷
2024年5月-至今 南方科技大學生物醫學工程系 副教授
2017年-2024年5月 南方科技大學生物醫學工程系 助理教授
2016年-2017年 美國里海大學生物工程 研究員
2009年-2016年 美國約翰霍普金斯大學生物醫學工程 博士后
獲獎及榮譽
2010-2013 美國關節炎基金博士后獎學金
研究興趣
郭瓊玉博士主要研究方向是開發納米至微米尺度新型形狀記憶性藥物釋放體系用于腫瘤治療和組織再生，其目標為從材料、細胞、動物實驗多個層面為解決具體的臨床問題設計一系列智能材料。
代表論文
1. Q. Guo, D. Miller, H. An, H. Wang, J. Lopez, D. Lough, L. He and A. Kumar, “Controlled heat stress promotes myofibrillogenesis during myogenesis,” PLoS ONE 11(11) (2016) e0166294.
2. S. Majumdar, Q. Guo, M. Garza-Madrid, X. Calderon-Colon, D. Duan, P. Carbajal, O. Schein, M. Trexler, and J. Elisseeff, “Influence of collagen source on fibrillar architecture and properties of vitrified collagen membranes”, J. Biomed. Mater. Res. Part B. 104B (2016) 300-307.
3. Q Guo, J.P. Mather, P. Yang, M. Boden, and P.T. Mather, “Fabrication of polymeric coatings with controlled microtopographies using an electrospraying technique,” PLoS ONE 10(6) (2015) e0129960.
4. S. Yang,# Q. Guo,# L. Shores, A. Aly, M. Ramakrishnan, G.-H. Kim, Q. Lu, L. Su, G. Zhao, J.H. Elisseeff, “Use of a chondroitin sulfate bioadhesive to enhance integration of bioglass particles for repairing critical-size bone defects,” J. Biomed. Mater. Res. Part A. 103A (2015) 235-242. (#= Co-first author)
5. Q. Guo, J.M. Phillip, S. Majumdar, P. Wu, J. Chen, X. Calderón-Colón, O. Schein, B.J. Smith, M.M. Trexler, D. Wirtz, and J.H. Elisseeff, “Modulation of keratocyte phenotype by collagen fibril nanoarchitecture in membranes for corneal repair,” Biomaterials 34 (2013) 9365-9372.
6. Q. Guo,# X. Wang,# M.W. Tibbitt, K.S. Anseth, D.J. Montell, and J.H. Elisseeff, “Light activated cell migration in synthetic extracellular matrices,” Biomaterials 33 (2012) 8040-8046. (#= Co-first author)
7. Q. Guo, A. Aly, O. Schein, M.M. Trexler, and J.H. Elisseeff, “Moxifloxacin in situ gelling microparticles-bioadhesive delivery system,” Results in Pharma. Sciences 2 (2012) 66-71.
8. A.T. Hillel, S. Unterman, Z. Nahas, B. Reid, J.M. Coburn, J. Axelman, J.J. Chae, Q. Guo, R. Trow, A. Thomas, Z. Hou, S. Lichtsteiner, D. Sutton, C. Matheson, P. Walker, N. David, S. Mori, J.M. Taube, and J.H. Elisseeff, “Photoactivated composite biomaterial for soft tissue restoration in rodents and in human,” Sci. Tranl. Med. 3, 93ra67 (2011) 1-12.
9. Q. Guo, P.T. Knight, J. Wu, and P.T. Mather, “Blends of paclitaxel with POSS-based biodegradable polyurethanes: morphology, miscibility, and specific interactions,” Macromolecules 43 (2010) 4991-4999.
10. Q. Guo, P.T. Knight, and P.T. Mather, “Tailored drug release from biodegradable stent coatings based on hybrid polyurethanes,” J. Control. Release 137 (2009) 224-233.
著書章節
1. Q. Guo, and J.H. Elisseeff, Cartilage Tissue Engineering, in: A. Atala, R. Lanza, J.A. Thomson, R. Nerem (Eds.), Principles of Regenerative Medicine, 2nd Ed, Elsevier, 2011, pp. 981-995.
專利申請
1. Q. Guo, J. Green, R.A. Meyer, C.J. Bishop, A. Kumar, and G.L. Semenza, “Shape memory particles for biomedical uses,” Patent application (WO2016164458A1) filed on April 6, 2016.
2. A. Kumar, D. Lough, C. Madsen, and Q. Guo, “Bone healing, angiogenesis-promoting and vasculogenesis-producing system,” Patent application (WO2016172004) filed on April 15, 2016.
3. J.H. Elisseeff, Q. Guo, and S. Majumdar, “Compositions comprising cyclodextrin incorporated collagen matrices for use in biomedical applications,” Patent application (US20170043021A1) filed on September 10, 2015.
4. J.H. Elisseeff, Q. Guo, S. Majumdar, and A. Singh, “Cornea mimetic biomaterials: vitrified collagen-cyclodextrin implants,” Patent Application (WO2016171745A1) filed on April 24, 2015.
5. M.M. Trexler, J.H. Elisseeff, D.G. Mulreany, Q. Guo, J.L. Breidenich, J.P. Maranchi, J.L. Graham, J.B. Patrone, M.W. Patchan, and X. Calderon-Colon, “Wound healing compositions comprising biocompatible cellulose hydrogel membranes and methods of use thereof,” Approved by USPTO on April 19, 2016. Patent #US9314531B2.